Morphea — Clinical Case (Wikimedia Commons)

Diagnosis: Morphea

Watercolour drawing of the face of a girl aged 16, who had two circumscribed patches of morphoea on her face. One extends upwards from the root of the left side of the nose in two streaks on to her fo. Clinical photograph sourced from Wikimedia Commons (CC BY 4.0). Attribution: Mark, Leonard Portal.

Clinical Presentation

Plaque morphea (most common): oval, indurated plaques with ivory-colored center and violaceous border ('lilac ring' indicates active inflammation). Linear morphea: band-like sclerosis, may cross joints causing contractures. En coup de sabre: linear forehead involvement.

Clinical History

More common in females, peak onset 20-50 years. No Raynaud or systemic sclerosis features. Linear morphea in children may affect underlying muscle and bone growth. Autoantibodies usually negative or low-titer ANA.

Treatment

Superficial plaque: topical corticosteroids, calcipotriene, tacrolimus, UVA1 phototherapy. Deep/linear/generalized: methotrexate + systemic corticosteroids (first-line). Mycophenolate for refractory. Physical therapy for linear morphea crossing joints.

Differential Diagnosis

Systemic sclerosis, Lichen sclerosus, Lipodermatosclerosis, Radiation-induced fibrosis, Eosinophilic fasciitis

Key Learnings

The 'lilac ring' indicates active, treatable disease — treatment should target this stage. Linear morphea in children can cause significant morbidity (limb length discrepancy, facial hemiatrophy). Morphea does NOT progress to systemic sclerosis.

Tags: morphea, localized scleroderma, sclerotic, autoimmune, fibrosis