Keloid — Clinical Case (Wikimedia Commons)

Diagnosis: Keloid

Keloids on arms caused by sulfuric acid. World War 2. 20th General Hospital.. Clinical photograph sourced from Wikimedia Commons (CC BY 2.0). Attribution: Otis Historical Archives of “National Museum of Health Medicine” (OTIS Archive 1).

Clinical Presentation

Firm, smooth, rubbery, shiny, raised scars extending beyond the wound border. Often pruritic or painful. Predilection sites: earlobes, chest, shoulders, upper back. Color ranges from flesh-colored to red to dark brown. May continue to grow over years.

Clinical History

Often follows trauma, surgery, piercings, burns, acne, or vaccination. More common in ages 10-30 and in patients of African, Asian, and Hispanic descent. Family history is common (autosomal dominant with variable penetrance).

Treatment

Intralesional triamcinolone (first-line, 10-40 mg/mL). Combination: excision + immediate post-op radiation or triamcinolone. Silicone sheets/gel. Cryotherapy. Pressure earrings post ear keloid excision. 5-FU intralesional injections.

Differential Diagnosis

Hypertrophic scar, Dermatofibrosarcoma protuberans, Dermatofibroma, Morphea

Key Learnings

Keloids extend BEYOND original wound borders (distinguishes from hypertrophic scars). Surgical excision alone has 50-100% recurrence rate — always combine with adjuvant therapy. Prevention in high-risk patients: pressure garments, silicone sheeting, avoid elective procedures.

Tags: keloid, scar, fibroproliferative, wound healing