Exanthem — Clinical Case (Wikimedia Commons)

Diagnosis: Exanthem

Exanthem that can sensitive people get as an allergic reaction on food (here chewing caramels Haribo Maoam). Clinical photograph sourced from Wikimedia Commons (Public domain). Attribution: Impetus.

Clinical Presentation

Typically symmetric, maculopapular eruption starting centrally and spreading peripherally. Specific patterns: cephalocaudal spread (measles), slapped-cheek (parvovirus B19), lacy reticular (fifth disease), blueberry muffin (congenital infections).

Clinical History

Prodromal symptoms (fever, malaise, URI symptoms), vaccination history, sick contacts, travel history, medication changes, immunocompromised status. Mucosal involvement (Koplik spots in measles).

Treatment

Usually self-limited. Supportive care with antipyretics, antihistamines for pruritus. Specific antivirals when indicated (acyclovir for varicella in immunocompromised). Immunoglobulin for measles in susceptible patients.

Differential Diagnosis

Morbilliform drug eruption, Viral exanthem, Scarlet fever, Secondary syphilis, Acute HIV, Kawasaki disease

Key Learnings

The six classic childhood exanthems should be recognized clinically. Drug eruptions must be excluded — timing relative to new medications is key. Mucosal involvement may suggest more serious diagnoses.

Tags: exanthem, viral, maculopapular, infectious