LICHEN AMYLOIDOSIS

Diagnosis: LICHEN AMYLOIDOSIS

Case submitted by Dr.Azeem Alam Khan to the dermRounds community.

Clinical Presentation

Clinical photograph(s) submitted for peer review and discussion.

Clinical History

Submitted by Dr.Azeem Alam Khan. Originally posted May 13, 2009.

Treatment

See case discussion.

Differential Diagnosis

• Lichen simplex chronicus • Prurigo nodularis • Hypertrophic lichen planus • Notalgia paresthetica

Key Learnings

• Primary cutaneous amyloidosis — amyloid derived from keratin • Intensely pruritic, hyperpigmented, hyperkeratotic papules on pretibial shins • "Rippled" or "corrugated" pattern • Common in Southeast Asian populations • Congo red: apple-green birefringence under polarized light • NOT associated with systemic (AL) amyloidosis

Tags: lichen, amyloidosis, dr.azeem alam khan