Gianotti Crosti syndrome

Diagnosis: Gianotti Crosti syndrome

Case submitted by Shahbaz A. Janjua to the dermRounds community.

Clinical Presentation

Clinical photograph(s) submitted for peer review and discussion.

Clinical History

Submitted by Shahbaz A. Janjua. Originally posted March 10, 2010.

Treatment

See case discussion.

Differential Diagnosis

• Papular acrodermatitis of childhood (variant) • Viral exanthem • Scabies • Papular urticaria • Langerhans cell histiocytosis • Lichen planus • Erythema multiforme

Key Learnings

• Also known as papular acrodermatitis of childhood • Symmetrical, monomorphic, papular eruption on face, buttocks, and extensor extremities • Originally associated with HBV infection; now commonly linked to EBV, CMV, and other viruses • Trunk typically spared — key clinical feature • Self-limited, resolving in 2-8 weeks • Lichenoid, flat-topped papules — may be flesh-colored, pink, or violaceous • Check hepatitis serology if clinically indicated

Tags: gianotti, crosti, syndrome, shahbaz a. janjua