Epidermoid Cyst (scrotum)

Diagnosis: Epidermoid Cyst (scrotum)

Multiple, firm, round nodules on the scrotum.

Clinical Presentation

Multiple, firm, round nodules on the scrotum.

Clinical History

Submitted by Alaa Saad. Originally posted October 14, 2010.

Treatment

See case discussion.

Differential Diagnosis

• Pilar (trichilemmal) cyst • Lipoma • Dermoid cyst • Abscess • Dermatofibroma • Pilomatricoma

Key Learnings

• Most common cutaneous cyst — lined by stratified squamous epithelium with granular layer • Central punctum is a helpful clinical clue • Rupture → intense foreign body reaction — NOT infection in most cases • Multiple epidermoid cysts: consider Gardner syndrome (APC mutation) • Pilar cyst: scalp predilection, lacks granular layer

Tags: epidermoid, cyst, scrotum, alaa saad