Discoid Lupus Erythematosus

Diagnosis: Discoid Lupus Erythematosus

Atrophic hypopigmented plaque with adherent, thick scales and scarring alopecia.

Clinical Presentation

Atrophic hypopigmented plaque with adherent, thick scales and scarring alopecia.

Clinical History

Submitted by Alaa Saad. Originally posted September 23, 2010.

Treatment

See case discussion.

Differential Diagnosis

• Subacute cutaneous lupus erythematosus • Psoriasis • Lichen planus • Tinea faciei • Granuloma annulare • Sarcoidosis • Morphea • Actinic keratosis

Key Learnings

• Most common form of chronic cutaneous lupus — only ~5-10% progress to SLE • Classic triad: erythema, scale with follicular plugging, and atrophic scarring • Carpet tack sign: adherent scale with follicular plugging seen on underside of removed scale • Scarring alopecia is a significant complication — early treatment prevents permanent hair loss • DIF (lupus band test): granular deposits of IgG, IgM, IgA, and C3 at DEJ in lesional skin • Dyspigmentation (central hypopigmentation with peripheral hyperpigmentation) especially prominent in darker skin • More common in African Americans and women

Tags: discoid, lupus, erythematosus, alaa saad