Multiple Pedunculated Skin-Colored Papules in the Axilla

Diagnosis: Acrochordons (skin tags)

A 45-year-old female presents with multiple skin-colored pedunculated papules in the axillary region, which have been gradually increasing over the past year. The lesions are asymptomatic, and the patient expresses concern regarding their appearance. Clinical examination reveals typical features consistent with benign skin growths, commonly referred to as skin tags.

Clinical Presentation

A 45-year-old female presents with multiple skin-colored pedunculated papules in the axillary region, which have been gradually increasing over the past year. These lesions are asymptomatic, but the patient expresses concern regarding their appearance. On examination, several lesions are noted, varying in size and morphology, predominantly located in the axillae.Multiple lesions: Numerous skin-colored, pedunculated papules.Location: Primarily located in the axillary region.Size: Lesions range from 2 to 5 mm in diameter.Asymptomatic: No tenderness, itching, or discharge noted.Skin texture: Smooth surface with a soft consistency.

Clinical History

The patient reports that the lesions began appearing approximately one year ago, with no known triggers. She denies any history of trauma or irritation to the area. There have been no prior treatments attempted for these lesions. The patient has a family history of similar lesions, and her past medical history is unremarkable. She works as a teacher and has no known allergies. There is no significant social history or recent exposure to new products.Onset: Gradual onset over the past year.Triggers: No known triggers or associated factors.Prior treatments: No previous treatments undertaken.Family history: Positive for similar lesions in relatives.Past medical history: Unremarkable, no chronic illnesses.Social history: No significant lifestyle factors impacting skin health.

Treatment

Acute / First-Line ManagementExcision: Surgical removal of individual lesions is the most definitive treatment. This can be performed under local anesthesia.Cryotherapy: Liquid nitrogen can be applied to the base of the lesion for effective destruction.Electrosurgery: This technique can be used for removal, particularly for larger lesions.Snip excision: A simple technique using scissors to remove the lesion at its base.Workup and Diagnostic ConfirmationClinical diagnosis: Typically, these lesions are diagnosed clinically based on appearance and location.Histopathology: Rarely needed, but can be performed if there is diagnostic uncertainty or atypical features.Long-Term ManagementObservation: No treatment is necessary for asymptomatic lesions.Patient education: Patients should be informed about the benign nature of the lesions.Monitoring: Regular follow-up may be warranted to assess for changes in appearance or symptoms.

Differential Diagnosis

Skin tags: Characterized by soft, pedunculated lesions, typically found in skin folds.Dermatofibroma: Firm, raised lesions often with a brownish hue, more commonly found on the extremities.Acrochordon-like lesions: May occur in conditions like Gardner's syndrome, which presents with multiple skin tags and other skin findings.Warts (Verrucae): Caused by HPV, these are often rough and can be painful, differing in texture from skin tags.Nevi: Common moles that can be pigmented or non-pigmented, typically not pedunculated.Basal cell carcinoma: Rarely, may mimic skin tags but often has additional features such as translucency or ulceration.Pyogenic granuloma: Often presents as a rapidly growing, red lesion that bleeds easily, usually not pedunculated.

Key Learnings

High-Yield PearlsCommonality: Acrochordons are extremely common benign lesions, especially in middle-aged individuals.Location: Frequently found in skin folds such as the axillae, neck, and groin.Asymptomatic nature: These lesions are typically asymptomatic and are removed for cosmetic reasons.Simple removal: Various removal techniques are effective, including snip excision and cryotherapy.Benign course: They do not progress to malignancy, reinforcing their benign nature.Acrochordons are benign skin lesions that often require no treatment unless for cosmetic concern.

Tags: skin tags, acrochordons