Capillary hemangioma, histopathology, low mag.

Diagnosis: Capillary hemangioma, histopathology, low mag.

Case submitted by dermRounds Dermatology Network to the dermRounds community.

Clinical Presentation

Clinical photograph(s) submitted for peer review and discussion.

Clinical History

Submitted by dermRounds Dermatology Network. Originally posted June 27, 2008.

Treatment

See case discussion.

Differential Diagnosis

• Vascular malformation • Kaposiform hemangioendothelioma • Tufted angioma • Pyogenic granuloma • Kaposi sarcoma • Neuroblastoma (metastatic) • Myofibroma

Key Learnings

• Infantile hemangioma: most common tumor of infancy — GLUT1 positive • Classic phases: proliferative (0-12 months) → plateau → involution (years) • Complete involution in ~50% by age 5, ~90% by age 9 • PHACES syndrome: large facial hemangiomas with posterior fossa, hemangioma, arterial, cardiac, eye, sternal defects • Alarming locations requiring treatment: periocular (amblyopia), airway (subglottic), ulcerated, large facial • Propranolol is the first-line treatment for problematic infantile hemangiomas — revolutionary since 2008 • Timolol 0.5% gel (topical) for small, superficial lesions

Tags: capillary, hemangioma, histopathology, low, mag, dermrounds dermatology network