Nevus Sebaceus

Diagnosis: Nevus Sebaceus

A mammillated alopecic plaque.

Clinical Presentation

A mammillated alopecic plaque.

Clinical History

Submitted by Alaa Saad. Originally posted September 14, 2010.

Treatment

See case discussion.

Differential Diagnosis

• Epidermal nevus • Aplasia cutis • Juvenile xanthogranuloma • Pilomatricoma • Dermoid cyst

Key Learnings

• Nevus sebaceus of Jadassohn — hamartoma of sebaceous glands, hair follicles, and apocrine glands • Yellow-orange, hairless, verrucous plaque on scalp or face — present from birth • Three phases: childhood (flat, hairless patch), puberty (thickened, verrucous), adulthood (risk of secondary tumors) • Risk of secondary neoplasms: trichoblastoma (most common), syringocystadenoma papilliferum, BCC (lower risk than historically believed) • Prophylactic excision is controversial — current evidence suggests lower malignancy risk than previously thought

Tags: nevus, sebaceus, alaa saad