Kaposi Sarcoma (classic type)

Diagnosis: Kaposi Sarcoma (classic type)

keratotic purplish macules, papules and nodules have arisen on the dorsum of the foot.

Clinical Presentation

keratotic purplish macules, papules and nodules have arisen on the dorsum of the foot.

Clinical History

Submitted by Alaa Saad. Originally posted January 18, 2011.

Treatment

See case discussion.

Differential Diagnosis

• Bacillary angiomatosis • Pyogenic granuloma • Angiosarcoma • Hemangioma • Dermatofibroma • Melanoma • Stasis dermatitis

Key Learnings

• Caused by HHV-8 (Human Herpesvirus 8) in all variants • Four types: classic (elderly Mediterranean men), endemic (sub-Saharan Africa), iatrogenic (immunosuppression), epidemic (HIV/AIDS) • HIV-associated KS: dramatically decreased with effective ART • Patch → plaque → nodular stage progression • Classic KS: indolent course, lower extremity predominance • Histology: spindle cell proliferation with slit-like vascular channels, PAS+ eosinophilic globules

Tags: kaposi, sarcoma, classic, type, alaa saad